FMOC-DL-(PHENYL)GLY-OH(Fmoc-DL-phenylglycine) is a chemical agent. The following is a description of its nature, use, preparation and safety information:
Nature:
FMOC-DL-(PHENYL)GLY-OH is a white or white-like solid with strong phenylglycine properties. It is soluble in some organic solvents, such as methanol, dimethyl sulfoxide and dichloromethane, but insoluble in water.
Use:
FMOC-DL-(PHENYL)GLY-OH is mainly used for peptide synthesis in organic synthesis. It is often used as a reagent to protect amino acids and is used to synthesize amino acids with hidden protecting groups in the peptide chain. This reagent can be prepared by reacting an amine group with an amino acid with a Fmoc-Cl (difluoromethanoyl chloride).
Method:
The FMOC-DL-(PHENYL)GLY-OH can be prepared by the following steps:
1. Dissolve DL-phenylglycine in sodium bicarbonate solution.
2. Add Fmoc-Cl and start the reaction.
3. The product was purified by extraction, drying and crystallization.
Safety Information:
Pay attention to safety measures when using FMOC-DL-(PHENYL)GLY-OH. It may cause irritation and damage to the skin, eyes and respiratory system. Therefore, appropriate personal protective equipment such as lab gloves and goggles should be worn during operation. At the same time, it should be operated in a well-ventilated place to avoid inhaling its gas or dust. During use and storage, it should be separated from oxidants and other combustibles. If an accident occurs, immediately flush the affected area with plenty of water and seek medical help.